Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling

Rationale: Protein acetylation is tightly linked to transcriptional control and energy metabolism. However, the role of protein acetylation in islet function remains enigmatic. This study aims to determine how protein acetylation controls β-cell function and explore the underlying mechanism. Methods...

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Detalles Bibliográficos
Autores principales: Zhang, Yuqing, Wang, Shushu, Zhang, Linlin, Zhou, Feiye, Zhu, Kecheng, Zhu, Qin, Liu, Qianqian, Liu, Yun, Jiang, Lei, Ning, Guang, Bi, Yufang, Zhou, Libin, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330849/
https://www.ncbi.nlm.nih.gov/pubmed/32641996
http://dx.doi.org/10.7150/thno.44459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330849/
https://www.ncbi.nlm.nih.gov/pubmed/32641996
http://dx.doi.org/10.7150/thno.44459

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