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Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling
Rationale: Protein acetylation is tightly linked to transcriptional control and energy metabolism. However, the role of protein acetylation in islet function remains enigmatic. This study aims to determine how protein acetylation controls β-cell function and explore the underlying mechanism. Methods...
Autores principales: | Zhang, Yuqing, Wang, Shushu, Zhang, Linlin, Zhou, Feiye, Zhu, Kecheng, Zhu, Qin, Liu, Qianqian, Liu, Yun, Jiang, Lei, Ning, Guang, Bi, Yufang, Zhou, Libin, Wang, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330849/ https://www.ncbi.nlm.nih.gov/pubmed/32641996 http://dx.doi.org/10.7150/thno.44459 |
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