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Bacterial extracellular vesicle-coated multi-antigenic nanovaccines protect against drug-resistant Staphylococcus aureus infection by modulating antigen processing and presentation pathways

Background: Vaccination provides an alternative to antibiotics in addressing drug-resistant Staphylococcus aureus (S. aureus) infection. However, vaccine potency is often limited by a lack of antigenic breadth and a demand on the generation of antibody responses alone. Methods: In this study, bacter...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Bai, Yanan, Li, Zhenzhen, Wang, Fei, Fan, Xuelian, Zhou, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330855/
https://www.ncbi.nlm.nih.gov/pubmed/32641983
http://dx.doi.org/10.7150/thno.44564