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Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis

Intrarenal calcium oxalate (CaOx) crystals induce renal tubular epithelial cells (TECs) injury and inflammation, which involve Toll-like receptor 4 (TLR4)/interferon regulatory factor 1 (IRF1) signaling. Additionally, infiltrating macrophages (Mϕs) might influence intrarenal CaOx crystals and CaOx-i...

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Detalles Bibliográficos
Autores principales: Liu, Haoran, Yang, Xiaoqi, Tang, Kun, Ye, Tao, Duan, Chen, Lv, Peng, Yan, Libin, Wu, Xiaoliang, Chen, Zhiqiang, Liu, Jianhe, Deng, Yaoliang, Zeng, Guohua, Xing, Jinchun, Ye, Zhangqun, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330860/
https://www.ncbi.nlm.nih.gov/pubmed/32641994
http://dx.doi.org/10.7150/thno.44054