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P2X7 receptors exert a permissive effect on the activation of presynaptic AMPA receptors in rat trigeminal caudal nucleus glutamatergic nerve terminals

BACKGROUND: Purine receptors play roles in peripheral and central sensitization and are associated with migraine headache. We investigated the possibility that ATP plays a permissive role in the activation of AMPA receptors thus inducing Glu release from nerve terminals isolated from the rat trigemi...

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Detalles Bibliográficos
Autores principales: Currò, Diego, Navarra, Pierluigi, Samengo, Irene, Martire, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330953/
https://www.ncbi.nlm.nih.gov/pubmed/32615921
http://dx.doi.org/10.1186/s10194-020-01153-y