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USMPep: universal sequence models for major histocompatibility complex binding affinity prediction

BACKGROUND: Immunotherapy is a promising route towards personalized cancer treatment. A key algorithmic challenge in this process is to decide if a given peptide (neoepitope) binds with the major histocompatibility complex (MHC). This is an active area of research and there are many MHC binding pred...

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Detalles Bibliográficos
Autores principales: Vielhaben, Johanna, Wenzel, Markus, Samek, Wojciech, Strodthoff, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330990/
https://www.ncbi.nlm.nih.gov/pubmed/32615972
http://dx.doi.org/10.1186/s12859-020-03631-1