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Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways

BACKGROUND: Phyllanthus amarus has been shown to attenuate lipopolysaccharide (LPS)-induced peripheral inflammation but similar studies in the central nervous system are scarce. The aim of the present study was to investigate the neuroprotective effects of 80% ethanol extract of P. amarus (EPA) in L...

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Detalles Bibliográficos
Autores principales: Ismail, Elysha Nur, Jantan, Ibrahim, Vidyadaran, Sharmili, Jamal, Jamia Azdina, Azmi, Norazrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330992/
https://www.ncbi.nlm.nih.gov/pubmed/32611404
http://dx.doi.org/10.1186/s12906-020-02961-0