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SM22α(+) vascular mural cells are essential for vessel stability in tumors and undergo phenotype transition regulated by Notch signaling

BACKGROUND: Malformation of blood vessels represents a hallmark of cancers, but the role and regulation of vascular mural cells (vMCs), including vascular smooth muscle cells (vSMCs) and pericytes, in tumors has not been fully understood. SM22α has been identified as a marker of vSMCs. This study ai...

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Detalles Bibliográficos
Autores principales: Zhang, Xinxin, Yan, Xianchun, Cao, Jing, Yang, Ziyan, Cao, Xiuli, Zhang, Yufei, Liang, Liang, Zheng, Minhua, Liu, Xiaowei, Zhang, Jian, Han, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331127/
https://www.ncbi.nlm.nih.gov/pubmed/32616053
http://dx.doi.org/10.1186/s13046-020-01630-x