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Dual indexed library design enables compatibility of in-Drop single-cell RNA-sequencing with exAMP chemistry sequencing platforms

BACKGROUND: The increasing demand of single-cell RNA-sequencing (scRNA-seq) experiments, such as the number of experiments and cells queried per experiment, necessitates higher sequencing depth coupled to high data quality. New high-throughput sequencers, such as the Illumina NovaSeq 6000, enables t...

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Detalles Bibliográficos
Autores principales: Southard-Smith, Austin N., Simmons, Alan J., Chen, Bob, Jones, Angela L., Ramirez Solano, Marisol A., Vega, Paige N., Scurrah, Cherie’ R., Zhao, Yue, Brenan, Michael J., Xuan, Jiekun, Shrubsole, Martha J., Porter, Ely B., Chen, Xi, Brenan, Colin J. H., Liu, Qi, Quigley, Lauren N. M., Lau, Ken S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331155/
https://www.ncbi.nlm.nih.gov/pubmed/32616006
http://dx.doi.org/10.1186/s12864-020-06843-0