Changes in relative histone abundance and heterochromatin in αA-crystallin and αB-crystallin knock-in mutant mouse lenses

OBJECTIVE: Understanding the mechanisms of cataract formation is important for age-related and hereditary cataracts caused by mutations in lens protein genes. Lens proteins of the crystallin gene families α-, β-, and γ-crystallin are the most abundant proteins in the lens. Single point mutations in...

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Detalles Bibliográficos
Autores principales: Andley, Usha P., Naumann, Brittney N., Hamilton, Paul D., Bozeman, Stephanie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331185/
https://www.ncbi.nlm.nih.gov/pubmed/32616056
http://dx.doi.org/10.1186/s13104-020-05154-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331185/
https://www.ncbi.nlm.nih.gov/pubmed/32616056
http://dx.doi.org/10.1186/s13104-020-05154-7

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