CDK4/6 inhibition enhances pulmonary inflammatory infiltration in bleomycin-induced lung fibrosis

Inhibitors of cyclin-dependent kinases 4/6 (CDK4/6) block cell cycle progression and are commonly used for treatment of several forms of cancer. Due to their anti-proliferative mode of action, we hypothesized that palbociclib could attenuate the development of bleomycin-induced lung fibrosis. In a p...

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Detalles Bibliográficos
Autores principales: Birnhuber, Anna, Egemnazarov, Bakytbek, Biasin, Valentina, Bonyadi Rad, Ehsan, Wygrecka, Malgorzata, Olschewski, Horst, Kwapiszewska, Grazyna, Marsh, Leigh M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331186/
https://www.ncbi.nlm.nih.gov/pubmed/32616042
http://dx.doi.org/10.1186/s12931-020-01433-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331186/
https://www.ncbi.nlm.nih.gov/pubmed/32616042
http://dx.doi.org/10.1186/s12931-020-01433-w

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