Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome

Marfan syndrome (MFS) is a heritable disorder of connective tissue, caused by mutations in the fibrillin-1 gene. Pulmonary functional abnormalities, such as emphysema and restrictive lung diseases, are frequently observed in patients with MFS. However, the pathogenesis and molecular mechanism of pul...

Descripción completa

Detalles Bibliográficos
Autores principales: Jespersen, Kathryn, Liu, Zhibo, Li, Chenxin, Harding, Paul, Sestak, Kylie, Batra, Rishi, Stephenson, Christopher A., Foley, Ryan T., Greene, Harrison, Meisinger, Trevor, Baxter, B. Timothy, Xiong, Wanfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331498/
https://www.ncbi.nlm.nih.gov/pubmed/32616814
http://dx.doi.org/10.1038/s41598-020-67941-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331498/
https://www.ncbi.nlm.nih.gov/pubmed/32616814
http://dx.doi.org/10.1038/s41598-020-67941-3

Ejemplares similares