High throughput single cell analysis of mitochondrial heteroplasmy in mitochondrial diseases

Mitochondrial heteroplasmy, which fundamentally means intracellular heterogeneity of mitochondrial DNA (mtDNA), has been measured in a group of cells, regardless of intercellular heterogeneity. Ordinal methods for mitochondrial heteroplasmy cannot discriminate between an intercellular homogenic popu...

Descripción completa

Detalles Bibliográficos
Autores principales: Maeda, Ryotaro, Kami, Daisuke, Maeda, Hideki, Shikuma, Akira, Gojo, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331593/
https://www.ncbi.nlm.nih.gov/pubmed/32616755
http://dx.doi.org/10.1038/s41598-020-67686-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331593/
https://www.ncbi.nlm.nih.gov/pubmed/32616755
http://dx.doi.org/10.1038/s41598-020-67686-z

Ejemplares similares