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Induced pluripotent stem cells of patients with Tetralogy of Fallot reveal transcriptional alterations in cardiomyocyte differentiation

Patient-specific induced pluripotent stem cells (ps-iPSCs) and their differentiated cell types are a powerful model system to gain insight into mechanisms driving early developmental and disease-associated regulatory networks. In this study, we use ps-iPSCs to gain insights into Tetralogy of Fallot...

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Detalles Bibliográficos
Autores principales: Grunert, Marcel, Appelt, Sandra, Schönhals, Sophia, Mika, Kerstin, Cui, Huanhuan, Cooper, Ashley, Cyganek, Lukas, Guan, Kaomei, Sperling, Silke R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331606/
https://www.ncbi.nlm.nih.gov/pubmed/32616843
http://dx.doi.org/10.1038/s41598-020-67872-z