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Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis

We elucidated the molecular cross-talk between cartilage and synovium in osteoarthritis, the most widespread arthritis in the world, using the powerful tool of single-cell RNA-sequencing. Multiple cell types were identified based on profiling of 10,640 synoviocytes and 26,192 chondrocytes: 12 distin...

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Detalles Bibliográficos
Autores principales: Chou, Ching-Heng, Jain, Vaibhav, Gibson, Jason, Attarian, David E., Haraden, Collin A., Yohn, Christopher B., Laberge, Remi-Martin, Gregory, Simon, Kraus, Virginia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331607/
https://www.ncbi.nlm.nih.gov/pubmed/32616761
http://dx.doi.org/10.1038/s41598-020-67730-y