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Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis
We elucidated the molecular cross-talk between cartilage and synovium in osteoarthritis, the most widespread arthritis in the world, using the powerful tool of single-cell RNA-sequencing. Multiple cell types were identified based on profiling of 10,640 synoviocytes and 26,192 chondrocytes: 12 distin...
Autores principales: | Chou, Ching-Heng, Jain, Vaibhav, Gibson, Jason, Attarian, David E., Haraden, Collin A., Yohn, Christopher B., Laberge, Remi-Martin, Gregory, Simon, Kraus, Virginia B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331607/ https://www.ncbi.nlm.nih.gov/pubmed/32616761 http://dx.doi.org/10.1038/s41598-020-67730-y |
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