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Phosphorylated peptide of G protein-coupled receptor induces dimerization in activated arrestin

Termination of the G-protein-coupled receptor signaling involves phosphorylation of its C-terminus and subsequent binding of the regulatory protein arrestin. In the visual system, arrestin-1 preferentially binds to photoactivated and phosphorylated rhodopsin and inactivates phototransduction. Here,...

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Detalles Bibliográficos
Autores principales: Stadler, Andreas M., Granzin, Joachim, Cousin, Anneliese, Batra-Safferling, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331637/
https://www.ncbi.nlm.nih.gov/pubmed/32616825
http://dx.doi.org/10.1038/s41598-020-67944-0