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PCDH7 interacts with GluN1 and regulates dendritic spine morphology and synaptic function

The N-terminal domain (NTD) of the GluN1 subunit (GluN1-NTD) is important for NMDA receptor structure and function, but the interacting proteins of the GluN1-NTD are not well understood. Starting with an unbiased screen of ~ 1,500 transmembrane proteins using the purified GluN1-NTD protein as a bait...

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Detalles Bibliográficos
Autores principales: Wang, Yuanyuan, Kerrisk Campbell, Meghan, Tom, Irene, Foreman, Oded, Hanson, Jesse E., Sheng, Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331671/
https://www.ncbi.nlm.nih.gov/pubmed/32616769
http://dx.doi.org/10.1038/s41598-020-67831-8