Lysophosphatidic acid modulates ovarian cancer multicellular aggregate assembly and metastatic dissemination

Epithelial ovarian cancer (EOC) metastasis occurs by exfoliation of cells and multicellular aggregates (MCAs) from the tumor into the peritoneal cavity, adhesion to and retraction of peritoneal mesothelial cells and subsequent anchoring. Elevated levels of lysophosphatidic acid (LPA) have been linke...

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Detalles Bibliográficos
Autores principales: Klymenko, Yuliya, Bos, Brandi, Campbell, Leigh, Loughran, Elizabeth, Liu, Yueying, Yang, Jing, Kim, Oleg, Stack, M. Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331713/
https://www.ncbi.nlm.nih.gov/pubmed/32616784
http://dx.doi.org/10.1038/s41598-020-67565-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331713/
https://www.ncbi.nlm.nih.gov/pubmed/32616784
http://dx.doi.org/10.1038/s41598-020-67565-7

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