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Lysophosphatidic acid modulates ovarian cancer multicellular aggregate assembly and metastatic dissemination
Epithelial ovarian cancer (EOC) metastasis occurs by exfoliation of cells and multicellular aggregates (MCAs) from the tumor into the peritoneal cavity, adhesion to and retraction of peritoneal mesothelial cells and subsequent anchoring. Elevated levels of lysophosphatidic acid (LPA) have been linke...
Autores principales: | Klymenko, Yuliya, Bos, Brandi, Campbell, Leigh, Loughran, Elizabeth, Liu, Yueying, Yang, Jing, Kim, Oleg, Stack, M. Sharon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331713/ https://www.ncbi.nlm.nih.gov/pubmed/32616784 http://dx.doi.org/10.1038/s41598-020-67565-7 |
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