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Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic–ischaemic brain injury: a single laboratory meta-analysis

Therapeutic hypothermia (HT) is standard care for term infants with hypoxic–ischaemic (HI) encephalopathy. However, the efficacy of HT in preclinical models, such as the Vannucci model of unilateral HI in the newborn rat, is often greater than that reported from clinical trials. Here, we report a me...

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Detalles Bibliográficos
Autores principales: Wood, Thomas R., Gundersen, Julia K., Falck, Mari, Maes, Elke, Osredkar, Damjan, Løberg, Else Marit, Sabir, Hemmen, Walløe, Lars, Thoresen, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331720/
https://www.ncbi.nlm.nih.gov/pubmed/32616806
http://dx.doi.org/10.1038/s41598-020-67532-2