Effects of pirfenidone targeting the tumor microenvironment and tumor-stroma interaction as a novel treatment for non-small cell lung cancer

Targeting cancer-associated fibroblasts (CAFs), as well as the crosstalk between stroma and cancer cells, could be of value in managing cancers. Pirfenidone (PFD) is an anti-fibrotic agent for idiopathic pulmonary fibrosis. This study aimed to investigate the possibility that PFD might exert an anti...

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Detalles Bibliográficos
Autores principales: Fujiwara, Ayako, Funaki, Soichiro, Fukui, Eriko, Kimura, Kenji, Kanou, Takashi, Ose, Naoko, Minami, Masato, Shintani, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331721/
https://www.ncbi.nlm.nih.gov/pubmed/32616870
http://dx.doi.org/10.1038/s41598-020-67904-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331721/
https://www.ncbi.nlm.nih.gov/pubmed/32616870
http://dx.doi.org/10.1038/s41598-020-67904-8

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