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Total Functional Score of Enhancer Elements Identifies Lineage-Specific Enhancers That Drive Differentiation of Pancreatic Cells

The differentiation of embryonic stem cells into various lineages is highly dependent on the chromatin state of the genome and patterns of gene expression. To identify lineage-specific enhancers driving the differentiation of progenitors into pancreatic cells, we used a previously described computat...

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Detalles Bibliográficos
Autores principales: Malladi, Venkat S., Nagari, Anusha, Franco, Hector L, Kraus, W Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331761/
https://www.ncbi.nlm.nih.gov/pubmed/32655276
http://dx.doi.org/10.1177/1177932220938063