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Total Functional Score of Enhancer Elements Identifies Lineage-Specific Enhancers That Drive Differentiation of Pancreatic Cells
The differentiation of embryonic stem cells into various lineages is highly dependent on the chromatin state of the genome and patterns of gene expression. To identify lineage-specific enhancers driving the differentiation of progenitors into pancreatic cells, we used a previously described computat...
Autores principales: | Malladi, Venkat S., Nagari, Anusha, Franco, Hector L, Kraus, W Lee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331761/ https://www.ncbi.nlm.nih.gov/pubmed/32655276 http://dx.doi.org/10.1177/1177932220938063 |
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