A systems-biology approach to molecular machines: Exploration of alternative transporter mechanisms

Motivated by growing evidence for pathway heterogeneity and alternative functions of molecular machines, we demonstrate a computational approach for investigating two questions: (1) Are there multiple mechanisms (state-space pathways) by which a machine can perform a given function, such as cotransp...

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Detalles Bibliográficos
Autores principales: George, August, Bisignano, Paola, Rosenberg, John M., Grabe, Michael, Zuckerman, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331975/
https://www.ncbi.nlm.nih.gov/pubmed/32614821
http://dx.doi.org/10.1371/journal.pcbi.1007884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331975/
https://www.ncbi.nlm.nih.gov/pubmed/32614821
http://dx.doi.org/10.1371/journal.pcbi.1007884

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