Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function

Interruption of the programmed death 1 (PD-1) / programmed death ligand 1 (PD-L1) pathway is an established and effective therapeutic strategy in human oncology and holds promise for veterinary oncology. We report the generation and characterization of monoclonal antibodies specific for canine PD-1...

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Detalles Bibliográficos
Autores principales: Choi, Jin Wook, Withers, Sita S., Chang, Hong, Spanier, Justin A., De La Trinidad, Victoria L., Panesar, Harmanpreet, Fife, Brian T., Sciammas, Roger, Sparger, Ellen E., Moore, Peter F., Kent, Michael S., Rebhun, Robert B., McSorley, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332054/
https://www.ncbi.nlm.nih.gov/pubmed/32614928
http://dx.doi.org/10.1371/journal.pone.0235518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332054/
https://www.ncbi.nlm.nih.gov/pubmed/32614928
http://dx.doi.org/10.1371/journal.pone.0235518

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