A framework for integrating directed and undirected annotations to build explanatory models of cis-eQTL data

A longstanding goal of regulatory genetics is to understand how variants in genome sequences lead to changes in gene expression. Here we present a method named Bayesian Annotation Guided eQTL Analysis (BAGEA), a variational Bayes framework to model cis-eQTLs using directed and undirected genomic ann...

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Detalles Bibliográficos
Autores principales: Lamparter, David, Bhatnagar, Rajat, Hebestreit, Katja, Belgard, T. Grant, Zhang, Alice, Hanson-Smith, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332077/
https://www.ncbi.nlm.nih.gov/pubmed/32516306
http://dx.doi.org/10.1371/journal.pcbi.1007770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332077/
https://www.ncbi.nlm.nih.gov/pubmed/32516306
http://dx.doi.org/10.1371/journal.pcbi.1007770

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