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A framework for integrating directed and undirected annotations to build explanatory models of cis-eQTL data
A longstanding goal of regulatory genetics is to understand how variants in genome sequences lead to changes in gene expression. Here we present a method named Bayesian Annotation Guided eQTL Analysis (BAGEA), a variational Bayes framework to model cis-eQTLs using directed and undirected genomic ann...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332077/ https://www.ncbi.nlm.nih.gov/pubmed/32516306 http://dx.doi.org/10.1371/journal.pcbi.1007770 |