Decipher the complexity of cis-regulatory regions by a modified Cas9

BACKGROUND: Understanding complex mechanisms of human transcriptional regulation remains a major challenge. Classical reporter studies already enabled the discovery of cis-regulatory elements within the non-coding DNA; however, the influence of genomic context and potential interactions are still la...

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Detalles Bibliográficos
Autores principales: Kirchner, Steven, Reuter, Stefanie, Westphal, Anika, Mrowka, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332081/
https://www.ncbi.nlm.nih.gov/pubmed/32614871
http://dx.doi.org/10.1371/journal.pone.0235530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332081/
https://www.ncbi.nlm.nih.gov/pubmed/32614871
http://dx.doi.org/10.1371/journal.pone.0235530

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