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Prostaglandin D2 signaling in dendritic cells is critical for the development of EAE

Priming of autoreactive T cells in lymph nodes by dendritic cells (DCs) is critical for the pathogenesis of experimental autoimmune encephalitis (EAE). DC activation reflects a balance of pro- and anti-inflammatory signals. One anti-inflammatory factor is prostaglandin D2 signaling through its cogna...

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Detalles Bibliográficos
Autores principales: Zheng, Jian, Sariol, Alan, Meyerholz, David, Zhang, Qinran, Abrahante Lloréns, Juan E., Narumiya, Shuh, Perlman, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332282/
https://www.ncbi.nlm.nih.gov/pubmed/32624353
http://dx.doi.org/10.1016/j.jaut.2020.102508