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Automated task training and longitudinal monitoring of mouse mesoscale cortical circuits using home cages

We report improved automated open-source methodology for head-fixed mesoscale cortical imaging and/or behavioral training of home cage mice using Raspberry Pi-based hardware. Staged partial and probabilistic restraint allows mice to adjust to self-initiated headfixation over 3 weeks’ time with ~50%...

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Detalles Bibliográficos
Autores principales: Murphy, Timothy H, Michelson, Nicholas J, Boyd, Jamie D, Fong, Tony, Bolanos, Luis A, Bierbrauer, David, Siu, Teri, Balbi, Matilde, Bolanos, Federico, Vanni, Matthieu, LeDue, Jeff M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332290/
https://www.ncbi.nlm.nih.gov/pubmed/32412409
http://dx.doi.org/10.7554/eLife.55964