Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

Ubiquitin ligases (E3s) embedded in the endoplasmic reticulum (ER) membrane regulate essential cellular activities including protein quality control, calcium flux, and sterol homeostasis. At least 25 different, transmembrane domain (TMD)-containing E3s are predicted to be ER-localised, but for most...

Descripción completa

Detalles Bibliográficos
Autores principales: Fenech, Emma J, Lari, Federica, Charles, Philip D, Fischer, Roman, Laétitia-Thézénas, Marie, Bagola, Katrin, Paton, Adrienne W, Paton, James C, Gyrd-Hansen, Mads, Kessler, Benedikt M, Christianson, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332293/
https://www.ncbi.nlm.nih.gov/pubmed/32614325
http://dx.doi.org/10.7554/eLife.57306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332293/
https://www.ncbi.nlm.nih.gov/pubmed/32614325
http://dx.doi.org/10.7554/eLife.57306

Ejemplares similares