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Evolutionarily conserved regulation of immunity by the splicing factor RNP-6/PUF60

Splicing is a vital cellular process that modulates important aspects of animal physiology, yet roles in regulating innate immunity are relatively unexplored. From genetic screens in C. elegans, we identified splicing factor RNP-6/PUF60 whose activity suppresses immunity, but promotes longevity, sug...

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Detalles Bibliográficos
Autores principales: Kew, Chun, Huang, Wenming, Fischer, Julia, Ganesan, Raja, Robinson, Nirmal, Antebi, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332298/
https://www.ncbi.nlm.nih.gov/pubmed/32538777
http://dx.doi.org/10.7554/eLife.57591