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NSM00158 Specifically Disrupts the CtBP2-p300 Interaction to Reverse CtBP2-Mediated Transrepression and Prevent the Occurrence of Nonunion

Carboxyl-terminal binding proteins (CtBPs) are transcription regulators that control gene expression in multiple cellular processes. Our recent findings indicated that overexpression of CtBP2 caused the repression of multiple bone development and differentiation genes, resulting in atrophic nonunion...

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Detalles Bibliográficos
Autores principales: Chen, Xun, Zhang, Wentao, Zhang, Qian, Song, Tao, Yu, Zirui, Li, Zhong, Duan, Ning, Dang, Xiaoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332362/
https://www.ncbi.nlm.nih.gov/pubmed/32434298
http://dx.doi.org/10.14348/molcells.2020.0042