Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome
BACKGROUND: Obesity and its associated diseases are major health problems characterized by extensive metabolic disturbances. Understanding the causal connections between these phenotypes and variation in metabolite levels can uncover relevant biology and inform novel intervention strategies. Recent...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332400/ https://www.ncbi.nlm.nih.gov/pubmed/32467615 http://dx.doi.org/10.1038/s41366-020-0603-x |