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Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection

Coronavirus disease 2019 (COVID-19) has become a worldwide threat to humans, and neutralizing antibodies have therapeutic potential. We have purified more than 1,000 memory B cells specific to SARS-CoV-2 S1 or its RBD (receptor binding domain) and obtain 729 paired heavy- and light-chain fragments....

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Detalles Bibliográficos
Autores principales: Wan, Jinkai, Xing, Shenghui, Ding, Longfei, Wang, Yongheng, Gu, Chenjian, Wu, Yanling, Rong, Bowen, Li, Cheng, Wang, Siqing, Chen, Kun, He, Chenxi, Zhu, Dandan, Yuan, Songhua, Qiu, Chengli, Zhao, Chen, Nie, Lei, Gao, Zhangzhao, Jiao, Jingyu, Zhang, Xiaoyan, Wang, Xiangxi, Ying, Tianlei, Wang, Haibin, Xie, Youhua, Lu, Yanan, Xu, Jianqing, Lan, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332464/
https://www.ncbi.nlm.nih.gov/pubmed/32668215
http://dx.doi.org/10.1016/j.celrep.2020.107918