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The neural stem-cell marker CD24 is specifically upregulated in IDH-mutant glioma

BACKGROUND: Malignant gliomas have disproportionally high morbidity and mortality. Heterozygous mutations in the isocitrate dehydrogenase 1 (IDH1) gene are most common in glioma, resulting in predominantly arginine to histidine substitution at codon 132. Because IDH1(R132H) requires a wild-type alle...

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Detalles Bibliográficos
Autores principales: Tiburcio, Patricia D.B., Locke, Mary C., Bhaskara, Srividya, Chandrasekharan, Mahesh B., Huang, L. Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332530/
https://www.ncbi.nlm.nih.gov/pubmed/32622311
http://dx.doi.org/10.1016/j.tranon.2020.100819