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The neural stem-cell marker CD24 is specifically upregulated in IDH-mutant glioma
BACKGROUND: Malignant gliomas have disproportionally high morbidity and mortality. Heterozygous mutations in the isocitrate dehydrogenase 1 (IDH1) gene are most common in glioma, resulting in predominantly arginine to histidine substitution at codon 132. Because IDH1(R132H) requires a wild-type alle...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332530/ https://www.ncbi.nlm.nih.gov/pubmed/32622311 http://dx.doi.org/10.1016/j.tranon.2020.100819 |