A programmable CRISPR/Cas9-based phage defense system for Escherichia coli BL21(DE3)

Escherichia coli BL21 is arguably the most popular host for industrial production of proteins, and industrial fermentations are often plagued by phage infections. The CRISPR/Cas system is guided by a gRNA to cleave a specific DNA cassette, which can be developed into a highly efficient programable p...

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Detalles Bibliográficos
Autores principales: Liu, Li, Zhao, Dongdong, Ye, Lijun, Zhan, Tao, Xiong, Bin, Hu, Muzi, Bi, Changhao, Zhang, Xueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332536/
https://www.ncbi.nlm.nih.gov/pubmed/32620105
http://dx.doi.org/10.1186/s12934-020-01393-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332536/
https://www.ncbi.nlm.nih.gov/pubmed/32620105
http://dx.doi.org/10.1186/s12934-020-01393-2

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