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CRISPR-Cas12a-Assisted Genome Editing in Amycolatopsis mediterranei
Amycolatopsis mediterranei U32 is an industrial producer of rifamycin SV, whose derivatives have long been the first-line antimycobacterial drugs. In order to perform genetic modification in this important industrial strain, a lot of efforts have been made in the past decades and a homologous recomb...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332547/ https://www.ncbi.nlm.nih.gov/pubmed/32671053 http://dx.doi.org/10.3389/fbioe.2020.00698 |