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In situ metabolomics in nephrotoxicity of aristolochic acids based on air flow-assisted desorption electrospray ionization mass spectrometry imaging

Understanding of the nephrotoxicity induced by drug candidates is vital to drug discovery and development. Herein, an in situ metabolomics method based on air flow-assisted desorption electrospray ionization mass spectrometry imaging (AFADESI-MSI) was established for direct analysis of metabolites i...

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Detalles Bibliográficos
Autores principales: Wang, Zhonghua, He, Bingshu, Liu, Yaqi, Huo, Meiling, Fu, Wenqing, Yang, Chunyan, Wei, Jinfeng, Abliz, Zeper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332651/
https://www.ncbi.nlm.nih.gov/pubmed/32642414
http://dx.doi.org/10.1016/j.apsb.2019.12.004