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Platinum complexes of curcumin delivered by dual-responsive polymeric nanoparticles improve chemotherapeutic efficacy based on the enhanced anti-metastasis activity and reduce side effects

Platinum-based chemotherapy is used for non-small cell lung cancer (NSCLC). However, it has side effects and minimum efficacy against lung cancer metastasis. In this study, platinum–curcumin complexes were loaded into pH and redox dual-responsive nanoparticles (denoted as Pt–CUR@PSPPN) to facilitate...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Chen, Chen, Zhang, Xiaojuan, He, Chuanchuan, Zhao, Pengxuan, Li, Minsi, Fan, Ting, Yan, Ruicong, Lu, Yao, Lee, Robert J., Khan, Muhammad Waseem, Sarfraz, Muhammad, Ma, Xiang, Yang, Tan, Xiang, Guangya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332658/
https://www.ncbi.nlm.nih.gov/pubmed/32642416
http://dx.doi.org/10.1016/j.apsb.2019.10.011