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Mismatch Repair Pathway, Genome Stability and Cancer

The acquisition of genomic instability is one of the key characteristics of the cancer cell, and microsatellite instability (MSI) is an important segment of this phenomenon. This review aims to describe the mismatch DNA repair (MMR) system whose deficiency is responsible for MSI and discuss the cell...

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Detalles Bibliográficos
Autores principales: Pećina-Šlaus, Nives, Kafka, Anja, Salamon, Iva, Bukovac, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332687/
https://www.ncbi.nlm.nih.gov/pubmed/32671096
http://dx.doi.org/10.3389/fmolb.2020.00122