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Pre-treatment With PLGA/Silibinin Nanoparticles Mitigates Dacarbazine-Induced Hepatotoxicity

Drug-induced hepatotoxicity is one of the major barriers limiting application of current pharmaceuticals as well as clinical translation of novel and perspective drugs. In this context, numerous hepatoprotective molecules have been proposed to prevent or mitigate drug-induced hepatotoxicity. To date...

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Detalles Bibliográficos
Autores principales: Durymanov, Mikhail, Permyakova, Anastasia, Reineke, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332747/
https://www.ncbi.nlm.nih.gov/pubmed/32671024
http://dx.doi.org/10.3389/fbioe.2020.00495