The construction of in vitro nasal cavity-mimic M-cell model, design of M cell-targeting nanoparticles and evaluation of mucosal vaccination by nasal administration

In order to better evaluate the transport effect of nanoparticles through the nasal mucosa, an in vitro nasal cavity-mimic model was designed based on M cells. The differentiation of M cells was induced by co-culture of Calu-3 and Raji cells in invert model. The ZO-1 protein staining and the transpo...

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Detalles Bibliográficos
Autores principales: Yang, Xiaotong, Chen, Xianchun, Lei, Ting, Qin, Lin, Zhou, Yang, Hu, Chuan, Liu, Qingfeng, Gao, Huile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332807/
https://www.ncbi.nlm.nih.gov/pubmed/32642415
http://dx.doi.org/10.1016/j.apsb.2020.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332807/
https://www.ncbi.nlm.nih.gov/pubmed/32642415
http://dx.doi.org/10.1016/j.apsb.2020.02.011

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