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Solid Dispersion Pellets: An Efficient Pharmaceutical Approach to Enrich the Solubility and Dissolution Rate of Deferasirox

Deferasirox (DFX) is an oral iron-chelating agent and classified into class II of the Biopharmaceutics Classification System. Low bioavailability of the drug due to insufficient solubility in physiological fluids is the main drawback of DFX. The idea of the current study was to explore the potential...

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Detalles Bibliográficos
Autores principales: Farmoudeh, Ali, Rezaeiroshan, Anahita, Abbaspour, Mohammadreza, Nokhodchi, Ali, Ebrahimnejad, Pedram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333047/
https://www.ncbi.nlm.nih.gov/pubmed/32685534
http://dx.doi.org/10.1155/2020/8583540