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Oltipraz Prevents High Glucose-Induced Oxidative Stress and Apoptosis in RSC96 Cells through the Nrf2/NQO1 Signalling Pathway

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM). Schwann cell (SC) apoptosis contributes to the occurrence and development of DPN. Effective drugs to prevent SC apoptosis are required to relieve and reverse peripheral nerve injury caused by DM. Oltipraz [4-met...

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Detalles Bibliográficos
Autores principales: Jiang, Zengxin, Bian, Mengxuan, Wu, Jingping, Li, Defang, Ding, Lei, Zeng, Qingmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333049/
https://www.ncbi.nlm.nih.gov/pubmed/32685505
http://dx.doi.org/10.1155/2020/5939815