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Polydatin relieves paraquat-induced human MRC-5 fibroblast injury through inhibiting the activation of the NLRP3 inflammasome

BACKGROUND: Paraquat (PQ) is a herbicide that is highly toxic to the lungs and kidneys. When it enters the body, it will disrupt the balance of the microenvironment in the body, induce a large number of inflammatory factors and cause cell damage. Polydatin (PD), resveratrol glycoside, has multiple p...

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Detalles Bibliográficos
Autores principales: Fu, Yue, Yan, Mei, Xie, Chunming, Hu, Jinlun, Zeng, Xiangxia, Hu, Qiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333108/
https://www.ncbi.nlm.nih.gov/pubmed/32647690
http://dx.doi.org/10.21037/atm-20-4570