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Long non-coding RNA LINC00426 contributes to doxorubicin resistance by sponging miR-4319 in osteosarcoma

BACKGROUND: LINC00426 is a newly identified long non-coding RNA (lncRNA) with unacknowledged biological roles. Here we set out to characterize the expression status of LINC00426 in osteosarcoma and understand its mechanistic involvement in incidence of doxorubicin (Dox) resistance. METHODS: The rela...

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Detalles Bibliográficos
Autores principales: Wang, Lulin, Luo, Yi, Zheng, Yiquan, Zheng, Lifeng, Lin, Wenxiang, Chen, Zonglin, Wu, Shichun, Chen, Jinhong, Xie, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333256/
https://www.ncbi.nlm.nih.gov/pubmed/32620145
http://dx.doi.org/10.1186/s13062-020-00265-4