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Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1

BACKGROUND: Some multifunctional cellular proteins, as the monocyte chemotactic protein-induced protein 1 (ZC3H12A/MCPIP1) and the cyclin-dependent kinase inhibitor CDKN1A/p21, are able to modulate the cellular susceptibility to the human immunodeficiency virus type 1 (HIV-1). Several studies showed...

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Detalles Bibliográficos
Autores principales: de Azevedo, Suwellen S. D., Ribeiro-Alves, Marcelo, Côrtes, Fernanda H., Delatorre, Edson, Spangenberg, Lucia, Naya, Hugo, Seito, Leonardo N., Hoagland, Brenda, Grinsztejn, Beatriz, Veloso, Valdilea G., Morgado, Mariza G., Souza, Thiago Moreno L., Bello, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333275/
https://www.ncbi.nlm.nih.gov/pubmed/32615986
http://dx.doi.org/10.1186/s12977-020-00522-4