Analysis of H3K4me3 and H3K27me3 bivalent promotors in HER2+ breast cancer cell lines reveals variations depending on estrogen receptor status and significantly correlates with gene expression

BACKGROUND: The role of histone modifications is poorly characterized in breast cancer, especially within the major subtypes. While epigenetic modifications may enhance the adaptability of a cell to both therapy and the surrounding environment, the mechanisms by which this is accomplished remains un...

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Detalles Bibliográficos
Autores principales: Kaukonen, Damien, Kaukonen, Riina, Polit, Lélia, Hennessy, Bryan T., Lund, Riikka, Madden, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333309/
https://www.ncbi.nlm.nih.gov/pubmed/32620123
http://dx.doi.org/10.1186/s12920-020-00749-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333309/
https://www.ncbi.nlm.nih.gov/pubmed/32620123
http://dx.doi.org/10.1186/s12920-020-00749-2

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